Some Uninvestigated Directions of Computational Fluid Dynamics Studies for Flow Phenomena in the Human Body

Some Uninvestigated Directions of Computational Fluid Dynamics Studies for Flow Phenomena in the Human Body

Image based CFD has been widely investigated in blood flow studies and respiratory flow studies. Their major interests lied in so-called patient specific modeling and analysis for diagnosis and treatment planning in clinical medicine. Since geometry of flow tracts in the body is so complex, no one could build an all-in-one generic model for them. Fluid flow is extremely susceptible by global shape, physiological conditions, and even very minute irregularities of cardiovascular and respiratory flow tracts. Moreover, we have to place a stress on the biological side of the flow phenomena. Living system responds, adapts and even remodels itself according to mechanical conditions as well as changes of them. It is therefore necessary to consider those altering conditions and parameters when we try to draw physiologically and pathologically significant information from computational studies. In the seminar, I would like to show and discuss some uninvestigated aspects of CFD studies of flow phenomena in the body. They are pathological flows particularly due to infectious diseases such as malaria, parsimonious modelling of multiple branching flow tracts of respiratory system, and survey of the pathogenesis of cerebral aneurysm.
Conclusively, I would like to place a stress on the points that image based modelling in the CFD application to the biological flow field is undoubtedly the mandatory technology for the clinical diagnosis and treatment planning, though there remain so many problems particularly related physiological and/or pathological process. Extension of the application is necessary to targets that have never been intensively studied by computational mechanical method.